Journal Basic Info

  • Impact Factor: 1.809**
  • H-Index: 6
  • ISSN: 2474-1655
  • DOI: 10.25107/2474-1655
**Impact Factor calculated based on Google Scholar Citations. Please contact us for any more details.

Major Scope

  •  Cardio-Thoracic Surgery
  •  Cardiovascular Medicine
  •  Oncology Cases
  •  Biochemistry and Biostatistics
  •  Hepatology
  •  Palliative Care
  •  Anesthesiology and Pain Medicine
  •  Pediatrics


Citation: Ann Clin Case Rep. 2022;7(1):2208.DOI: 10.25107/2474-1655.2208

An Unusual Case of Congenital Herpes Simplex Virus Type-2 (HSV-2) in an Extremely Premature Infant

Sfurti Nath MD, Rana Alissa MD, and Renu Sharma MD*

Department of Pediatrics, Division of Neonatology, University of Florida Health Science Center, Jacksonville, USA

*Correspondance to: Renu Sharma 

 PDF  Full Text Case Report | Open Access


We report a case of congenital infection of Herpes Simplex Virus-2 (HSV-2) in an extremely premature infant born at 25 weeks of gestation presenting in unusual manner with hydrops, atypical, extensive, hemorrhagic bullous rash, hepatosplenomegaly, coagulopathy and multi-organ failure. Placental and autopsy investigations confirmed in-utero transmission of disseminated congenital HSV-2 infection without any maternal history of HSV.


Congenital HSV; Extreme prematurity; Hydops-fetalis

Cite the Article:

Nath S, Alissa R, Sharma R. An Unusual Case of Congenital Herpes Simplex Virus Type-2 (HSV-2) in an Extremely Premature Infant. Ann Clin Case Rep. 2022; 7: 2208..

Search Our Journal

Journal Indexed In

Articles in PubMed

Tocotrienols: Exciting Biological and Pharmacological Properties of Tocotrienols and other Naturally Occurring Compounds, Part I
 PubMed  PMC  PDF  Full Text
Does Autoimmunity have a Role in Myoclonic Astatic Epilepsy? A Case Report of Voltage Gated Potassium Channel Mediated Seizures
 PubMed  PMC  PDF  Full Text
View More...

Articles with Grants

Application of the “4S” Technique - A Modified Double- Incision Extracapsular Cataract Extraction Combined with IOL Implantation in a Senile Cataract Patient with Low Corneal Endothelial Cell Density: A Clinical Report
 Abstract  PDF  Full Text
FAM83D and Malignant Tumors: A Brief Literature Review
 Abstract  PDF  Full Text
View More...