ANCA-Associated Vasculitis Overlaps with Acute Cerebral Infarction: A Case Report

Fan X1,2, Wang X2 and Zhou X1,2*

1Department of Nephrology, Shanxi Provincial People’s Hospital, China
2The Fifth Clinical Medical College of Shanxi Medical University, China

^*Correspondance to: Xiaoshuang Zhou 

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Abstract:

Antineutrophil Cytoplasmic Antibody (ANCA) Associated Vasculitis (AAV) is a group of multisystem autoimmune small vessel diseases. We report a case of a 68-year-old woman who initially presented with bilateral numbness of her hands and feet over past 20 days and cranial MRI before hospitalization showed acute cerebral infarction in left basal ganglia, so was admitted to the department of neurology. Her symptoms persisted and blood tests indicated heart failure, renal impairment and evidence of an inflammatory response. Chest Computed Tomography (CT) scan and ANCA testing confirmed a diagnosis of AAV renal injury and then was transferred to the department of nephrology. She was treated with blood purification for four sessions, glucocorticoid and cyclophosphamide therapy at which time her kidney function had improved. This case study illustrates that the clinical manifestations of AVV are complex, varied, and prone to misdiagnosis.

Keywords:

ANCA; Vasculitis; ANCA-associated vasculitis; Acute cerebral infarction

Cite the Article:

Fan X, Wang X, Zhou X. ANCAAssociated Vasculitis Overlaps with Acute Cerebral Infarction: A Case Report. Ann Clin Case Rep. 2023; 8: 2549..