Helpful Deeds in Recurrent Hypopharyngeal Squamous Cell Carcinoma with Performed Surgical Treatment and Chemoradiotherapy

Stoyanov St1, Staykova J2, Ananoshtev N3 and Vizev S4

1University Specialized Hospital for an Active Treatment of Oncology (USBALO) – Sofia, Bulgaria
2Department of Preventive Medicine, Medical University – Sofia, Bulgaria
3Complex Oncological Centre – Plovdiv, Bulgaria
4Department of Preventive Medicine, Medical University – Sofia, Bulgaria

^*Correspondance to: Krasimir Vizev 

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Abstract:

Nevertheless, the progress in operative and chemo-radio-therapy way of treatment of hypopharyngeal squamous cell carcinoma, the last comes to be one of the worst cancers of head and neck – generally. Most of the patients with locally advanced such tumors could not be treated by organic (larynx) – saved operation with performed already chemoradiotherapy. We checked 53 patients with locally advanced hypopharyngeal squamous cell carcinoma, suitable for a total laryngectomy, being treated before by Doxetacel + Cisplatina + 5-Fluorouracil (5FU) – with a purpose to store the larynx. We analyzed 51 patients with advanced stages of hypopharyngeal carcinoma in order to detach the type of helpful neck dissection – a large, or a selective one. The mean time for declaring a recurrence from the beginning of the treatment is 10.3 months. The whole process of helpful deeds against recurrences was 45% (local-85%, local-regional-100%, regional-23%, distant-19%). We declared a reasonable cumulative survival – with non-activity tumor among the patients with performed extra operative and chemoradiotherapy, as well as lack of 3 years survival in those with only chemoradiotherapy, performed before. We declare, that using the induced chemo-therapy with Doxatel, Cisplatina, 5-Fluorouracil (5FU) on a base of larynx – saving method could be used successfully in a case of advanced hypopharyngeal carcinoma.

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Cite the Article:

Stoyanov St, Staykova J, Ananoshtev N, Vizev S. Helpful Deeds in Recurrent Hypopharyngeal Squamous Cell Carcinoma with Performed Surgical Treatment and Chemoradiotherapy. Ann Clin Case Rep. 2023; 8: 2376..