Inflammatory Myofibroblastic Tumor of the Abdominal Wall in an Adult Male: A Case Report and Literature Review

Nuerabula Wujimaimaiti#, Yi Wu#, Jingxiong Yuan and Renyi Qin*

Department of Biliary-Pancreatic Surgery, Affiliated Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, China
#These authors contributed equally to this work

^*Correspondance to: Renyi Qin 

 PDF  Full Text Case Report | Open Access

Abstract:

Background: Inflammatory Myofibroblastic Tumor (IMT) of the abdominal wall is an exceedingly rare entity and to our best knowledge, there are only 4 cases are reported in the English literature (excluding of this case). The clinical symptoms, treatment and prognosis of this tumor are still uncertain. Case Summary: A 49-year-old Chinese man was admitted to our hospital with approximately 45 mm palpable mass located in the abdominal wall, without any other systemic symptoms. Computed Tomography (CT) demonstrated a 41 mm × 23 mm abdominal wall mass that was well-limited, heterogenous enhancement in portal venous image. The lesion was resected and histopathologic examination revealed that the tumor was predominantly comprised of spindle cells arranged in myxoid stroma with an inflammatory infiltrate of lymphocytes, plasma cells and histiocytes. An immunohistochemical analysis demonstrated positive staining for vimentin, CD34, D2-40 and negative staining for Smooth Muscle Actin (SMA), desmin, S100, CD21, CD23, CD1α, HMB45, Melan-A, SOX10, Myogenin, STAT6, CD117. Hence, we had come to a diagnosis of IMT. The patient recovered well without any complications, and we had been followed up for the last 27 months without clinical or radiographic evidence of recurrence or metastasis. Conclusion: Since abdominal wall IMT is uncommon lesion and lacks characteristic clinical manifestation with uncertain biological behavior, we have great challenge to have a clear statement on preoperational diagnosis. Surgical resection remains the best option for diagnosis and treatment.

Keywords:

Inflammatory myofibroblastic tumor; Abdominal wall; Case report; Anaplastic lymphoma kinase; Diagnosis; Literature review

Cite the Article:

Wujimaimaiti N, Wu Y, Yuan J, Qin R. Inflammatory Myofibroblastic Tumor of the Abdominal Wall in an Adult Male: A Case Report and Literature Review. Ann Clin Case Rep. 2021; 6: 2068..