Treatment Recommendations of a Rare Neurological Paraneoplastic Syndrome Caused by Small Cell Lung Cancer: A Case Report

Wenxing Yan, Daoming Zhang, Wanze Zhang, Min Liu and Linlin Liu

Radiotherapy Department of Oncology, Second Hospital of Jilin University, Changchun 130021, People’s Republic of China

^*Correspondance to: Linlin Liu 

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Abstract:

Paraneoplastic syndrome refers to these pathological changes of far organ function of patients when malignancy do not metastasize. It would cause some relevant clinical manifestations in nerve, digestion, hematopoiesis, endocrine, bones, joints and urinary system. And when the lesions occur in nervous system, called the neurological Paraneoplastic Syndrome (PNS). PNS occurs with any type of malignancy although the more commonly tumors are Small-Cell Lung Cancer (SCLC). It appears generally earlier comparing with the clinical symptoms directly caused by the tumor. The diagnosis is difficult and the treatment is more difficult. Neurological dysfunction is severe. This paper reports a case of 59 year old male with PNS as the initial symptom of small cell lung cancer. The symptoms of PNS repeated attacks after surgery and chemotherapy, but the symptoms are serious, it is rare in clinical. After the multidisciplinary consultation, Symptoms of PNS in patients accepting the active treatment of the original disease and anti-depressant drugs and anti-pain drug treatment at the same time have eased, which has a certain reference value to the treatment of PNS.

Keywords:

Small cell lung cancer (SCLC); Paraneoplastic neurological syndromes (PNS); MDT (Multi-disciplinary team); Treatment

Cite the Article:

Yan W, Zhang D, Zhang W, Liu M, Liu L. Treatment Recommendations of a Rare Neurological Paraneoplastic Syndrome Caused by Small Cell Lung Cancer: A Case Report. Ann Clin Case Rep. 2017; 2: 1283.