Unveiling a Rare Case of Non-Pigmenting Subtype of Fixed Drug Eruption Induced by NSAID: A Case Report

Tooba Fida*, Usama Bin Shabbir, Maham Zaman and Gulelala Taha

Department of Cardiology, King Edward Medical University, Pakistan

^*Correspondance to: Tooba Fida 

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Abstract:

Fixed Drug Eruption (FDE) is a unique form of cutaneous drug reaction that typically reoccurs as single or multiple lesions in the same locations, when the offending drug is reintroduced, with each recurrence potentially involving additional sites. FDE can manifest as singular, scattered, or widespread lesions. The lesions can appear as blisters, vesicles or bullae, which rupture easily, resulting in erosions or shallow ulcers and heal with or without residual pigmentation. The culprit drugs associated with this condition are antimicrobial agents, antipyretic/anti-inflammatory analgesics, and medications used to treat the central nervous system disorders. It can also occur following exposure to Ultraviolet A or B (UVA/UVB) radiation, or even certain foods rather than drugs. We here present an uncommon case of a 14-year-old boy with a history of recurrent oral and genital ulcers, consistently appearing at the same locations after taking NSAIDS since 2021; the lesions respond to steroids. The biopsy report confirmed a diagnosis of fixed drug eruption induced by NSAID.

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Cite the Article:

Tooba Fida, Usama Bin Shabbir, Maham Zaman, Gulelala Taha. Unveiling a Rare Case of Non- Pigmenting Subtype of Fixed Drug Eruption Induced by NSAID: A Case Report. Ann Clin Case Rep. 2024; 9: 2678..