Case Report on Dexamethasone Induced Iatrogenic Cushing Syndrome

Gireesh KM*, Sushma Priya MS, Sanjeev M, Prajwal, Manjunatha R and Vinod N

Department of Pharmacy Practice, TVM College of Pharmacy, India

^*Correspondance to: Gireesh KM 

 PDF  Full Text Case Report | Open Access

Abstract:

Corticosteroids are the pharmacotherapeutics agents that are used to treat various autoimmune diseases. Prolonged use of corticoids can induce some specific side effects like iatrogenic Cushing syndrome (moon face, central obesity, plethora, buffalo hump). Sudden withdrawal of corticosteroids will lead to adrenal hypertrophy which releases insufficient cortisol into the blood and leads to adrenal crisis. Here, a 52 years old female patient experienced Cushing syndrome after taking dexamethasone tablet for prolonged period. She presented with all physical symptoms of Cushing syndrome. As patient is under adrenal crisis patient collapsed due to septic shock. The prominent ways to avoid these conditions are to provide patient counseling before initiating corticosteroids and warning the patient about sudden withdrawal of corticosteroids.

Keywords:

Iatrogenic Cushing syndrome; Corticosteroids; Dexamethasone; Adrenal crisis; Cortisol

Cite the Article:

Gireesh KM, Sushma Priya MS, Sanjeev M, Prajwal, Manjunatha R, Vinod N. Case Report on Dexamethasone Induced Iatrogenic Cushing Syndrome. Ann Clin Case Rep. 2023; 8: 2468..