Ocular Medulloepithelioma: Case Report and Literature Review

Alarcon Peralta EF1*, Heredia Zelaya A1, Rivera Carmelo PF1, Davila López KE1, Canovas FC1,2, Zambrano SC3 and Ocrospoma DV3

1Department of Radiotherapy, National Institute of Neoplastic Diseases, Peru
2BC Cancer – Kelowna, Sindi Ahluwalia Hawkins Centre, Canada
3Department of Pathology, National Institute of Neoplastic Diseases, Peru

^*Correspondance to: Elizabeth Fanny Alarcon Peralta 

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Abstract:

Medulloepithelioma is a congenital tumor of very low incidence, generally unilateral and rarely bilateral, with very few cases appearing in the global literature. It primarily develops in the ciliary body, and its diagnosis is differential, with retinoblastoma as the primary option for diagnosis. This is the first case of medulloepithelioma identified at the National Institute of Neoplastic Diseases in Lima, Peru, the leading cancer-treatment institution of the nation. A case report of a 4-year-old female with decrease of visual acuity and a spot-like lesion in her right eye, initially diagnosed as glaucoma and cataracts. In October of 2020, the patient was treated surgically with the removal of her right eye once the diagnosis of orbital Medulloepithelioma was confirmed. She had early recurrence three months later. A follow-up MRI confirms recurrence at the surgical bed level, as well as the presence of an ipsilateral parotid node with a metastasis biopsy that tests positive. The patient was subjected to orbit exenteration, right cervical dissection, and homolateral parotidectomy with skin graft. The pathology confirms the diagnosis of orbit medulloepithelioma in the lesion of the surgical site and the parotid region, while the nodal dissection did not report compromised nodes. She received adjuvant chemotherapy and concurrent chemoradiotherapy localized to the tumor bed and parotid region with a dose of 50 Gy in 25 sessions. Once this concurrence ends, she continues with chemotherapy.

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Cite the Article:

Alarcon Peralta EF, Heredia Zelaya A, Rivera Carmelo PF, Davila López KE, Canovas FC, Zambrano SC, et al. Ocular Medulloepithelioma: Case Report and Literature Review. Ann Clin Case Rep. 2022; 7: 2343..