Colorectal Cancer in Adolescence: A Report of Two Cases

Inès Ayadi1*, Basma Soussi2, Rim Kallel3, Hazem Ben Ameur4 and Afef Khanfir1

1Department of Medical Oncology, Habib Bourguiba Hospital University, University of Sfax, Tunisia
2Department of Radiology, Habib Bourguiba Hospital University, University of Sfax, Tunisia
3Pathology Laboratory, Habib Bourguiba Hospital University, University of Sfax, Tunisia
4Department of Surgery, Habib Bourguiba Hospital University, University of Sfax, Tunisia

^*Correspondance to: Inès Ayadi 

 PDF  Full Text Case Report | Open Access

Abstract:

Background: Colorectal cancer is very rare in children. Therefore, the diagnosis is generally established at advanced disease. This is a presentation of two cases of colorectal treated at Habib Bourguiba Hospital University. Case Report: Two adolescents, 14-year-old and 16-year-old were treated for CRC between 2006 and 2022 in our department. Both complained about abdominal and pelvic pain few months ago. The first patient, with no personal or family history of digestive pathology, was admitted for peritonitis. The exploration noted advanced rectal tumor, peritoneal carcinomatosis and bone metastasis. She had one cycle of palliative FOLFIRI chemotherapy and died. The other one was admitted for complicated appendicitis. Per-operative exploration noted localized sigmoid tumor which was resected. She had 12 cycles of adjuvant FOLFOX chemotherapy and she was alive and free failure for 13 years. Her paternal uncle had yet rectal cancer at 40 years and her father developed later metastatic colon cancer. Lynch syndrome was established. Conclusion: Colorectal cancer is rare in children. It can be sporadic or hereditary cancer. Diagnosis is often Tardive. The prognosis is tightly correlated to stage so any children presenting with chronic pain in abdomen with doubtful history of constipation and rectal bleeding should be carefully examined.

Keywords:

Cite the Article:

Ayadi I, Soussi B, Kallel R, Ameur HB, Khanfir A. Colorectal Cancer in Adolescence: A Report of Two Cases. Ann Clin Case Rep. 2022; 7: 2286..