Journal Basic Info

  • Impact Factor: 1.809**
  • H-Index: 6
  • ISSN: 2474-1655
  • DOI: 10.25107/2474-1655
**Impact Factor calculated based on Google Scholar Citations. Please contact us for any more details.

Major Scope

  •  Child Birth
  •  Endoscopy
  •  Gastric Cancer
  •  Anatomy
  •  Chronic Disease
  •  Lung Cancer
  •  Asthma
  •  Psychiatry and Mental Health


Citation: Ann Clin Case Rep. 2022;7(1):2224.DOI: 10.25107/2474-1655.2224

Herpes Zoster Ophthalmicus Reactivation after mRNA 1273 Vaccination

Ashraful Hoque1* and Hossain Imam2

1Department of Blood Transfusion, Sheikh Hasina National Institute of Burn & Plastic Surgery, Bangladesh 2Department of Burn & Plastic Surgery, Sheikh Hasina National Institute of Burn & Plastic Surgery, Bangladesh

*Correspondance to: Ashraful Hoque 

 PDF  Full Text Case Report | Open Access


Background: Clinically two different types of Varicella-Zoster Virus (VZV) infection are found commonly. Varicella (chickenpox) is caused by primary infection, and Herpes zoster, also known as shingles, is caused by reactivation of latent VZV that gained access to sensory ganglia during varicella. Reactivation is influenced by age-related immune-senescence, iatrogenic immunosuppression or disease-related immune-compromise state. As a vaccine can cause Immune Reconstitution Inflammatory Syndrome (IRIS), it can also reactivate VZS. Case Report: We discovered an elderly male (62 years old, Bangladeshi) with a painful blister around his right eyeball, as well as blurred vision in that eye. Examination found decreased visual acuity with hyperemia and edema in the eyelid and conjunctiva. He was found to have Herpes Zoster Ophthalmicus (HZO). Herpes zoster is a reactivation of the varicella-zoster virus, most commonly seen in the elderly and immunosuppressed, with incidence estimates ranging from 1.25 to 5.25 per 1,000 person-years showed in different studies. If patients are not treated promptly and aggressively, HZO with intraocular involvement can significantly impair visual vision. Our patient recovered entirely after getting proper treatment. Conclusion: No vaccine is 100% safe, and intense surveillance to assess the vaccine safety for the detection of any event which could attenuate the expected benefits, and thus to take any necessary action to minimize risks to vaccinated individuals.


Reactivation; Herpes Zoster Ophthalmicus; Immunocompromised; Vaccine

Cite the Article:

Hoque A, Imam H. Herpes Zoster Ophthalmicus Reactivation after mRNA 1273 Vaccination. Ann Clin Case Rep. 2022; 7: 2224..

Search Our Journal

Journal Indexed In

Articles in PubMed

Does Autoimmunity have a Role in Myoclonic Astatic Epilepsy? A Case Report of Voltage Gated Potassium Channel Mediated Seizures
 PubMed  PMC  PDF  Full Text
A New Minimally Invasive Procedure for Muscle, Back, Neck Pain and Radiculopathy - The Myofascial Nerve Block
 PubMed  PMC  PDF  Full Text
View More...

Articles with Grants

Risky Sexual Practice, Unintended Pregnancy, Contraceptive Utilization, and Its Determinants among HIV-Infected Women in Oromia Regional State, Ethiopia
 Abstract  PDF  Full Text
Case of Spinal Cord Injury Caused by Electrical Stimulation of Thoracic Spinal Cord for Treatment of Diabetic Foot
 PDF  Full Text
View More...