Journal Basic Info

  • Impact Factor: 1.809**
  • H-Index: 6
  • ISSN: 2474-1655
  • DOI: 10.25107/2474-1655
**Impact Factor calculated based on Google Scholar Citations. Please contact us for any more details.

Major Scope

  •  Radiology Cases
  •  Hepatitis
  •  Pathology
  •  Orthopedic Sugery
  •  Sleep Medicine and Disorders
  •  Internal Medicine
  •  Ophthalmology
  •  Pneumonia


Citation: Ann Clin Case Rep. 2022;7(1):2097.DOI: 10.25107/2474-1655.2097

Graves’ Ophthalmopathy Induced by Radioiodine Therapy for Toxic Thyroid Adenoma

Laura Delegido-Gomez1#, Soledad Serrano Corredor2, Paula Revert2 and Ruth Sanchez-Ortiga2*#

1Department of Endocrinology, Hospital Marina Baixa, Spain
2Department of Endocrinology, Hospital General Universitario de Alicante, Spain
#These authors equally contributed to this work

*Correspondance to: Ruth Sanchez-Ortiga 

 PDF  Full Text Case Report | Open Access


Graves’s Disease (GD) may develop as an infrequent adverse effect after radioiodine therapy for toxic thyroid adenoma and toxic multi nodular goiter. We present a case of a 64- year-old female treated with radioiodine therapy for toxic adenoma and subclinical hyperthyroidism, whose antithyroid peroxidase and TSH-Receptor Antibodies (TRAbs) were negatives. She didn’t smoke. After therapy, the patient became hyperthyroid and presented ophthalmopathy with positive TRAb. She underwent to corticosteroid and anti-thyroid treatment. After eighteen months of treatment, she maintained asymptomatic and TRAb were negatives. The radioiodine therapy for toxic adenoma may induce GD and thyroid ophthalmopathy even in absence of classical risks factors


Thyroid-associated orbitopathy; Graves’s disease; Radioiodine therapy; Thyroperoxidase antibody; Thyrotropin receptor antibodies; Thyroid toxic adenoma

Cite the Article:

Delegido-Gomez L, Corredor SS, Revert P, Sanchez-Ortiga R. Graves’ Ophthalmopathy Induced by Radioiodine Therapy for Toxic Thyroid Adenoma. Ann Clin Case Rep. 2022; 7: 2097..

Search Our Journal

Journal Indexed In

Articles in PubMed

A New Minimally Invasive Procedure for Muscle, Back, Neck Pain and Radiculopathy - The Myofascial Nerve Block
 PubMed  PMC  PDF  Full Text
Tocotrienols: Exciting Biological and Pharmacological Properties of Tocotrienols and other Naturally Occurring Compounds, Part I
 PubMed  PMC  PDF  Full Text
View More...

Articles with Grants

Patient Exposure Dose in a Videofluoroscopic Swallowing Study
 Abstract  PDF  Full Text
Partial Ground Glass Nodule with Irregular Followingup “Rapidly” Progressed to Refractory Advanced Lung Cancer: A Case Report
 Abstract  PDF  Full Text
View More...