Type 1 Cryoglobulinemia Secondary to Primary Plasma Cell Leukemia: A Rare Presentation of a Rare Entity

Antonio G Faieta1*, Madhupreet Kaur2 and Tawhida Khatoon2

1Department of Medical Oncology, The James Cancer Center, USA
2Department of Internal Medicine, Beaumont Health, USA

^*Correspondance to: Antonio G Faieta 

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Abstract:

Primary Plasma Cell Leukemia (pPCL) is a rare and aggressive form of plasma cell dyscrasia that comprises 1% of plasma cell dyscrasias. It is characterized by the presence of more than 20% plasma cells in the peripheral blood or an absolute peripheral blood plasma cell count of greater than 2.0 x 109 cells/L. Symptoms are similar to Multiple Myeloma (MM) but develop in a shorter period of time. A case of secondary plasma cell leukemia associated with type 1 cryoglobulinemia was reported in the literature. To our knowledge, this is the first case of pPCL with associated necrotizing lesions and cryoglobulin level up to 81%.

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Cite the Article:

Faieta AG, Kaur M, Khatoon T. Type 1 Cryoglobulinemia Secondary to Primary Plasma Cell Leukemia: A Rare Presentation of a Rare Entity. Ann Clin Case Rep. 2021; 6: 2029.