Overcome after Special Use of Bridging Therapy in Refractory DLBCL Subsequently Treated with CAR-T Cell

Cristina Prieto Prieto and Silvia Sequero-López

Department of Radiation Oncology, San Cecilio Clinical University Hospital, Spain Department of Medical Oncology, San Cecilio Clinical University Hospital, Spain These authors contributed equally to this work

^*Correspondance to: Cristina Prieto Prieto 

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Abstract:

Our case report is about a 63-year-old patient diagnosed with a refractory highly biologically aggressive cervical diffuse large B-cell lymphoma as malignant transformation from gastric follicular lymphoma. Meanwhile she was presented as a candidate for CAR-T treatment, due to clinical risk of airway obstruction by the tumor, she underwent an intensive bridge therapy based on radiotherapy concomitant with chemotherapy and targeted therapy in our center. As far as we know, these combinations of treatments have never been used before. Our objective is to show the good results in terms of response and survival in our patient after CAR-T cell infusion.

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Cite the Article:

Prieto CP, Sequero-López S. Overcome after Special Use of Bridging Therapy in Refractory DLBCL Subsequently Treated with CAR-T Cell. Ann Clin Case Rep. 2021; 6: 1917..