A Case Report of Serological Evidence of Paramyxoviruses Related to Porcine Orthorubulavirus in Mexican Bats

Cuevas-Romero S1,3*, Lara-Romero R1,2, Ramliden M3, Guerrero JA4, Mendoza HR5, Blomström AL3, Berg M3 and Cerriteño-Sánchez JL1*

1Centro Nacional de Investigación Disciplinaria en Salud Animal e Inocuidad, INIFAP, Mexico 2UNAM, México Posgrado en Ciencias de la Producción y de la Salud Animal, Mexico 3Department of Biomedical Sciences and Veterinary Public Health, Section of Virology, Swedish University of Agricultural Sciences, Sweden 4Laboratory of Systematics and Morphology, Autonomous University of the State of Morelos, Mexico 5Department of Microbiology and Immunology, UNAM, Mexico

^*Correspondance to: Cuevas-Romero S, Cerriteño-Sánchez JL 

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Abstract:

In this report, we showed the presence of antibodies to Porcine orthorubulavirus (PRV) in Mexican bats using a serological approach. A total of 42 bats, belonging to seven different species, were sampled from two different refuges/caves, located near to a pig fattening area where spontaneous outbreaks of PRV had occurred. Analysis by serum-virus neutralizing and immunoperoxidase monolayer assay revealed the presence of antibodies in fifteen out of 42 investigated bats (i.e. 35%), six of them were also positive by Paramyxoviridae family using PCR assay targeting the L gene of paramyxoviruses. This case demonstrates for the first time antibodies detection of this virus in different bats species which is important for our understanding of PRV ecology, evolution and mechanism of cross-species transmission. These findings support the hypothesis that bats could act as an intermediate or natural host for interspecies transmission of certain paramyxoviruses.

Keywords:

Porcine orthorubulavirus; Bats; Epidemiology; Inter-species transmission

Cite the Article:

Cuevas-Romero S, Lara-Romero R, Ramliden M, Guerrero JA, Mendoza HR, Blomström AL, et al. A Case Report of Serological Evidence of Paramyxoviruses Related to Porcine Orthorubulavirus in Mexican Bats. Ann Clin Case Rep. 2022; 7: 2177..