Cribriform-Morular Variant of Papillary Thyroid Carcinoma: Two Cases of a Rare Thyroid Cancer Associated with Familial Adenomatous Polyposis

Alejandro Perez, Sarah Findeis, Atin Agarwal, Julia Berry and Katie King

Department of Pathology, Texas A&M University College of Medicine, USA
Department of Pathology, Baylor University Medical Center, USA

^*Correspondance to: Alejandro Perez 

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Abstract:

Cribriform-Morular Variant of Papillary Thyroid Carcinoma (CMV-PTC) is an uncommon variant of Papillary Thyroid Carcinoma (PTC). CMV-PTC can be associated with Familial Adenomatous Polyposis (FAP), an autosomal dominant polyposis syndrome caused by a mutation in the APC gene which leads to a disruption of the Wnt/β-catenin pathway. Understanding the relationship between CMV-PTC and FAP is a diagnostic tool not only for pathologists, but also for clinicians as FAP has several implications for not only the patient, but the patient's family as well.

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Cite the Article:

Perez A, Findeis S, Agarwal A, Berry J, King K. Cribriform-Morular Variant of Papillary Thyroid Carcinoma: Two Cases of a Rare Thyroid Cancer Associated with Familial Adenomatous Polyposis. Ann Clin Case Rep. 2019; 4: 1612.