New Onset of Obsessive-Compulsive Disorder Post Cingulate Surgery for Refractory Epilepsy

Gheorghe A, Chamelian L and Maurice C

Department of Psychiatry, University of Toronto, Canada
Department of Psychiatry, University of Montreal, Canada
Department of Neurology, University of Toronto, Canada

^*Correspondance to: Catherine Maurice 

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Abstract:

We report the case of a 52 year-old man presenting obsessive-compulsive behaviors following a temporal anterior lobectomy in the context of refractory epilepsy. The patient’s evolution and management are discussed. We elaborate on the pathophysiology of OCD (obsessive-compulsive disorder) and the potential mechanisms explaining this unusual scenario. We focus mainly on the implication of various pathways, neurotransmitters and disruptions along the striatal-orbitofrontalthalamic interconnections.

Keywords:

Obsessive-complusive disorder; Refractory epilepsy; Structural epilepsy; Temporal epilepsy; Serotonin; Selective serotonin reuptake inhibitor; 5-HT

Cite the Article:

Gheorghe A, Chamelian L, Maurice C. New Onset of Obsessive-Compulsive Disorder Post Cingulate Surgery for Refractory Epilepsy. Ann Clin Case Rep. 2018; 3: 1541.