Journal Basic Info

  • Impact Factor: 1.809**
  • H-Index: 6
  • ISSN: 2474-1655
  • DOI: 10.25107/2474-1655
**Impact Factor calculated based on Google Scholar Citations. Please contact us for any more details.

Major Scope

  •  Cardio-Thoracic Surgery
  •  Trauma
  •  Women’s Health Care
  •  Surgery Cases
  •  Lung Cancer
  •  Anesthesiology and Pain Medicine
  •  Urology Cases
  •  Nutrition and Food Science


Citation: Ann Clin Case Rep. 2017;2(1):1396.DOI: 10.25107/2474-1655.1396

A Case of Bupropion-Induced Toxic Epidermal Necrolysis (TEN)

Temiz Selami Aykut, Dursun Recep, Daye Munise, Ataseven Arzu and Özer İlkay

Department of Dermatology, Meram Faculty of Medicine, Necmettin Erbakan University Konya, Turkey

*Correspondance to: Ataseven Arzu 

 PDF  Full Text Case Report | Open Access


Toxic Epidermal Necrolysis (TEN), which has high mortality, is an acute mucocutaneous disease with bullous lesions in the skin, eyes and mucosae. It often develops due to medications. Bupropion is an antidepressant that blocks neural dopamine and the noradrenaline reuptake. Its slow-release form is used in smoking cessation treatments. In the literature, Bupropion-induced side effects have been reported such as urticaria angioedema, erythema multiforme, and acute generalized eczematous pustulosis. We found it appropriate to present our case of Bupropion-induced toxic epidermal necrolysis, which has not yet been presented in the literature.


Toxic epidermal necrolysis; Urticarial; Bupropion; Immunoglobulin

Cite the Article:

Aykut TS, Recep D, Munise D, Arzu A, İlkay Ö. A Case of Bupropion-Induced Toxic Epidermal Necrolysis (TEN). Ann Clin Case Rep. 2017; 2: 1396. ISSN: 2474-1655.

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