False Acute Kidney Injury Alert due to Model Car Fuel Ingestion

Mohammad Al-Jubouri, Louise Hassal, Darren Powell and David Scholes

Department of Clinical Biochemistry, St. Helens and Knowsley Teaching Hospitals NHS Trust, United Kingdom
Department of Care of the Elderly, St. Helens and Knowsley Teaching Hospitals NHS Trust, United Kingdom

^*Correspondance to: Mohammad Al-Jubouri 

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Abstract:

We report a case of accidental ingestion of model car fuel (Optifuel) resulting in an apparent elevation of serum creatinine of 274 μmol/L (3.1 mg/dL) as measured by the Jaffe (alkaline picrate) reaction and this has generated an acute kidney injury (AKI) stage 3 alert. Optifuel contains nitromethane, which has been reported to interfere in the Jaffe reaction causing falsely high creatinine measurements. The laboratory staffs were vigilant about this potential interfering substance so have repeated the analysis of the creatinine using an enzymatic method which showed a result of 47 μmol/L (0.5 mg/ dL). This report highlights the importance of being aware of the limitations of biochemical tests to avoid misinterpretation of results.

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Cite the Article:

Al-Jubouri M, Hassal L, Powell D, Scholes D. False Acute Kidney Injury Alert due to Model Car Fuel Ingestion. Ann Clin Case Rep. 2017; 2: 1327.