Journal Basic Info

  • Impact Factor: 1.809**
  • H-Index: 6
  • ISSN: 2474-1655
  • DOI: 10.25107/2474-1655
**Impact Factor calculated based on Google Scholar Citations. Please contact us for any more details.

Major Scope

  •  Molecular Biology
  •  Gastric Cancer
  •  Oncology Cases
  •  Ophthalmology
  •  Depression
  •  Sports Medicine
  •  Surgery Cases
  •  Signs and Symptoms-Clinical Findings


Citation: Ann Clin Case Rep. 2022;7(1):2341.DOI: 10.25107/2474-1655.2341

Lobular Carcinoma In Situ within Fibroadenoma: A Case Report and Literature Review

Ye D1#, Zhou B2#, Wu L1#, Liu L1, Zhang Z1, Ye M1, Yang Y1, Wei F1, Zhang G1 and Qingwu L1*

1Department of Pathology, Nanchang First Hospital, Jiangxi Province 330008, China
2Department of Pathology, Dean Huaxing Medical Laboratory Co., Ltd, Jiangxi Province 330089, China
#These authors contributed equally to this work

*Correspondance to: Li Qingwu 

 PDF  Full Text Case Report | Open Access


Breast fibroadenoma is the most common tumor with benign biological behavior in women. However, the imaging and clinical features of carcinoma in situ within a fibroadenoma are often similar to those of a fibroadenoma. This study aimed to report the case of a 38-year-old young woman with a regular painless mass in her right breast for 6 years. This tumor had a clear boundary and was composed of epithelial and mesenchymal cells. Most of the area comprised the so-called fibroadenoma structure, besides swelling and proliferation in a small part of the terminal duct and no expression of E-cadherin protein. The histological morphology and immunohistochemistry confirmed the diagnosis of a fibroadenoma with lobular carcinoma in situ. We need to be careful of malignant transformation within fibroadenomas and improve the understanding of lobular carcinoma in situ within fibroadenoma.


Cite the Article:

Ye D, Zhou B, Wu L, Liu L, Zhang Z, Ye M, et al. Lobular Carcinoma In Situ within Fibroadenoma: A Case Report and Literature Review. Ann Clin Case Rep. 2022; 7: 2341.

Search Our Journal

Journal Indexed In

Articles in PubMed

Tocotrienols: Exciting Biological and Pharmacological Properties of Tocotrienols and other Naturally Occurring Compounds, Part I
 PubMed  PMC  PDF  Full Text
Does Autoimmunity have a Role in Myoclonic Astatic Epilepsy? A Case Report of Voltage Gated Potassium Channel Mediated Seizures
 PubMed  PMC  PDF  Full Text
View More...

Articles with Grants

Bilateral Anterior Ischemic Optic Neuropathy Following COVID-19 Vaccination in a Healthy Young Patient
 Abstract  PDF  Full Text
Predictive Factors for Pregnancy Termination Following a Prenatal Diagnosis of Down Syndrome: Experience from the Reunion Registry of Congenital Malformations from 2002 to 2015
 Abstract  PDF  Full Text
View More...