Fine Needle Aspiration Cytology and DNA Analysis by Flow- Cytometry of Atypical Medullary Breast Carcinoma: A Case Report

Trutin Ostović K, Čikara I, Žic R, Lipšanski Z and Lambaša S

Department of Clinical Cytology, Dubrava University Hospital, Zagreb, Croatia
Department of Radiology, Dubrava University Hospital, Zagreb, Croatia
Department of Plastic, Reconstructive and Esthetic Surgery Dubrava University Hospital, Zagreb, Croatia
Department of Molecular Biology, Clinical Unit of Cytology, Dubrava University Hospital, Zagreb, Croatia
Department of Pathology, Dubrava University Hospital, Zagreb, Croatia

^*Correspondance to: Trutin Ostovi? K 

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Abstract:

Atipycal medullary carcinoma is a rare breast carcinoma (less than 4%patients). We report a case of fine needle cytology of atypical medullary carcinoma. It was diagnosed in 43-years-old woman 18 years ago. She also suffered from Morbus Hashimoto and hypothireosis. The tumour was detected by mammography in the upper part of the left breast. Fine needle aspiration cytology with ultrasound guidance of the tumour was performed. Cytological diagnosis of poorly differentiated carcinoma of the breast was put. The patient was operated on (mastectomy) and histological diagnosis of atypical medullary carcinoma was put. The tumour was oestrogen and progesterone receptor negative. It was hyper dyploid with high proliferative activity by flow cytometric DNA analysis. The patient was without any sign of the tumour 15 years after the operation when she died because of the heart failure.

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Cite the Article:

Trutin Ostović K, Čikara I, Žic R, Lipšanski Z, Lambaša S. Fine Needle Aspiration Cytology and DNA Analysis by Flow- Cytometry of Atypical Medullary Breast Carcinoma: A Case Report. Ann Clin Case Rep. 2017; 2: 1313.