Journal Basic Info

  • Impact Factor: 1.809**
  • H-Index: 6
  • ISSN: 2474-1655
  • DOI: 10.25107/2474-1655
**Impact Factor calculated based on Google Scholar Citations. Please contact us for any more details.

Major Scope

  •  Transplantation Medicine
  •  Dentistry and Oral Biology
  •  Lung Cancer
  •  Hepatitis
  •  Molecular Biology
  •  Women’s Health Care
  •  Endoscopy
  •  Emergency Medicine and Critical Care


Citation: Ann Clin Case Rep. 2016;1(1):1095.DOI: 10.25107/2474-1655.1095

Giant Cell-rich Osteosarcoma in Temporal Bone: Case Report and Literature Review

Guo-Bin Hong, Qi-Lan Xu, Wen-Hao Wu, Xin-Min Gou and Ling-Jing Gu

Department of Radiology, Sun Yat-Sen University, China
Department of Pathology, Sun Yat-Sen University, China
Department of Radiology, Ji'nan University, China

*Correspondance to: Guo-Bin Hong 

 PDF  Full Text Case Report | Open Access


Objective: Describe the clinical, imageological, and pathological features of Giant cell-rich osteosarcoma (GCRO), as well as differential diagnosis.Case
Presentation: We describe a 43-year-old patient with temporal bone GCRO who accidentally noticed a painless hard bump about the size of a finger in the left tempus a year ago. Imageological examination showed obvious swelling of the temporal bone, dissolving bony destruction, invasive growth, wide range of involvement, and obvious enhancement of the substantial part of the tumor (found by enhancement scanning). Pathological studies also revealed a large number of osteoclastlike giant cells in the background of osteosarcoma.Conclusion: GCRO can be easily misdiagnosed as GCT, and early diagnosis is very important for its prognosis. Clinically and imageologically, GCRO has certain characteristics but lacks specificity; thus, clinical, imageological, and pathological diagnoses should be integrated.


Giant cell-rich osteosarcoma (GCRO); Osteosarcoma

Cite the Article:

Hong G-B, Xu Q-L, Wu W-H, Gou X-M, Gu L-J. Giant Cell-rich Osteosarcoma in Temporal Bone: Case Report and Literature Review. Ann Clin Case Rep. 2016; 1: 1095.

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