Ann Clin Case Rep | Volume 7, Issue 1 | Case Report | Open Access

Primary Urethral Carcinoma: A Case Report and Review of the Literature

Yuan Guo#, Guo Yang#, Yangbin Tang, Yongbo Zheng and Xiaohou Wu*

Department of Urology, The First Affiliated Hospital of Chongqing Medical University, China
#These authors contributed equally to this work

*Correspondance to: Xiaohou Wu 

Fulltext PDF


Primary urethral carcinoma is a kind of rare clinical disease, especially urethral multiple lesions in situ, and there has been far less emphasis on understanding the diagnosis and treatment for it. Here we reported a rare case of primary urethral carcinoma. The patient came to the urology clinic due to difficulty of urination for 3 months, aggravated with gross hematuria for 1 day. Cystoscopy founds multiple cauliflower-like neoplasm originating in the prostatic urethral, bulbous urethral and penile urethral. Moreover, there are condyloma acuminate and occasional urinary tract irritation medical history with the patient. Preoperative biopsy or postoperative pathology revealed high-grade urothelial carcinoma. The surgeon took tumor resection of urethra for the patient. And then the immunohistochemical analysis of the specimen was carried out and results confirmed the diagnosis. After the operation, 6 cycles of pirarubicin were implemented and there is no evidence show harmful reaction. During a 6-month follow-up, we find no evidence for tumor recurrence, metastasis or surgical complications. After all, primary urethral urothelium carcinoma is rare in clinical practice with particular clinical and pathological characteristics. There is still no mature treatment plan and should be studied further.


Guo Y, Yang G, Tang Y, Zheng Y, Wu X. Primary Urethral Carcinoma: A Case Report and Review of the Literature. Ann Clin Case Rep. 2022; 7: 2250..

Subscribe to Our Newsletter