Ann Clin Case Rep | Volume 7, Issue 1 | Case Report | Open Access

An Unexpected Cause of Chest Pain in a Patient with Closed Atrial Septal Defect

Bermudez-Gonzalez JL1,2, Villa-Ramírez CA1,2, Bautista-Pérez-Gavilán A1,2, Saenz-Ancira S1,3, Garcia-Cardenas M1, Gonzalez-Hernandez MA1, Ibarra-Moreno A1, Perez-Partida AM1, Arce- Sandoval CR2, Cuéllar-Vargas J2, Espinola-Zavaleta N1 and Alexanderson-Rosas E1,2*

1Department of Nuclear Cardiology, National Institute of Cardiology Ignacio Chavez, Mexico 2National Autonomous University of Mexico, Mexico 3La Salle University, Mexico

*Correspondance to: Alexanderson-Rosas E 

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Atrial Septal Defects (ASD) represent the most common Congenital Heart Diseases (CHD) in adults and are usually treated with the septal amplatzer occluders. Complications usually arise due to mechanical problems of the device and are traditionally investigated, nevertheless, other chest pain etiologies should be considered, as data regarding late complications like angina, are scarce and insufficient. We present the case of a 70 year-old woman with a closed ASD and coronary microvascular disease diagnosed during follow-up with gated Positron Emission Tomography (PET). Late complications associated with Amplatzer occluder devices are generally derived from a mechanical impairment of the device per se. The case presented opens the door for further research questions regarding microvascular complications arising from occluding devices.


Atrial septal disease; Congenital heart disease; Amplatzer septal occlude; Angina; Chest pain; Microvascular disease


Bermudez-Gonzalez JL, Villa-Ramírez CA, Bautista-Pérez-Gavilan A, Saenz-Ancira S, Garcia-Cardenas M, Gonzalez-Hernandez MA, et al. An Unexpected Cause of Chest Pain in a Patient with Closed Atrial Septal Defect. Ann Clin Case Rep. 2022; 7: 2175..

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