Hereditary Pancreatitis Associated with a Cationic Trypsinogen Mutation

Briongos-Figuero LS, Herrán-Monge R and Pérez-Castrillón JL

Internal Medicine Department.Rio Hortega University Hospital, Spain
Intensive Care Unit.Rio Hortega University Hospital, Spain

^*Correspondance to: Laisa Socorro Briongos-Figuero 

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Abstract:

Introduction: Hereditary pancreatitis is a very rare form of early pancreatitis with autosomal dominant pattern of inheritance. Follow-up is very important due to a markedly increased risk of pancreatic cancer.Case
Presentation: We report a case of a 22-year-old man with several episodes of acute recurrent pancreatitis, initially labeled as alcoholic related versus idiopathic but finally diagnosed of hereditary pancreatitis due a mutation in cationic trypsinogen gene.
Conclusion: Genetic testing should be considered in patients with unexplained recurrent pancreatitis at early age and family history of pancreatitis due to a markedly increased risk of pancreatic cancer. This rare case emphasizes upon considering this entity in the differential diagnosis of recurrent pancreatitis especially in young adult, genetic diagnosis and counselling during follow-up. Hereditary pancreatitis is a very rare form of early pancreatitis with autosomal dominant pattern of inheritance. Follow up is very important due to a markedly increased risk of pancreatic cancer. We report a case of a young man with episodes of acute recurrent pancreatitis, initially labeled as alcoholic related versus idiopathic but finally diagnosed of hereditary pancreatitis due a mutation in cationic trypsinogen gene.

Keywords:

Hereditary pancreatitis; Cationic trypsinogen; Genetic susceptibility; Recurrent acute pancreatitis

Cite the Article:

Briongos-Figuero LS, Herr�n-Monge R, P�rez-Castrill�n JL. Hereditary Pancreatitis Associated with a Cationic Trypsinogen Mutation. Ann Clin Case Rep. 2016; 1: 1086.