Functional Outcome of Intra-Articular Corticosteroid Injections for Knee Osteoarthritis in Bangladeshi Patients

Ghosh S1, Islam Khan Z2, Kumar Ghosh SR3, Ali MR4 and Rahman F5

1Departments of Orthopedic Surgery, Chittagong Medical College Hospital, Chittagong, Bangladesh
2Department of Biological and Biomedical Sciences, School of Health and Life Sciences, Glasgow Caledonian University, UK
3Departments of Orthopedic Surgery, Ad-din Women’s Medical College Hospital, Dhaka, Bangladesh
4Departments of Orthopedic, Chittagong Medical College Hospital, Chittagong, Bangladesh
5Department of Gynecology and Obstetrics, Zamzam Hospital Ltd, Cox’s Bazar, Bangladesh

^*Correspondance to: Md Zahidul Islam Khan 

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Abstract:

Introduction: Knee osteoarthritis is common joint disease, with an incidence of 30% of the population older than 60 years. Intra-articular injection of steroid is a common treatment option for osteoarthritis of the knee. However, there is scarcity of studies regarding the outcome of intraarticular corticosteroid therapy for osteoarthritis of knee joint. Therefore, the aim of this study was to evaluate the functional outcome of intra- articular corticosteroid injections for the management of knee osteoarthritis. Methodology: In this prospective hospital based clinical trial, patient >45 years of age presented with knee osteoarthritis (Kellgren Lawrence grades 1 to 3) was assigned. Study was conducted for six months from January 2022 to July 2022 in Chittagong Medical College Hospital. Total 30 samples were included in this study and follow up was done after 3 months. The overall functional outcomes were measured by Visual Analog Scale (VAS) and Oxford Knee Score. Data was analyzed by using windows-based computer software devised with SPSS-25. Results: In this study, out of 30 cases, 20 (66.7%) were male and 10 (33.3%) were female, there was male predominance with male to female ratio about 2:1. Majority of the cases (57.7%) was in 55 to 64 years of age group. The mean ± SD age of the cases was 56.83 ± 5.742 years (range: 45-69). Out of 30 cases, most of the cases {16 (53.3%)} were affected at left side. Before getting injection, both severe and very severe pain was observed among 13 (43.3%) patients and 4 (13.3%) patients had moderate pain. After 3 months of injection, there was no pain among 8 (26.7%) patients and 22 (73.3%) patients had mild pain according to VAS. Pre-injection group, 21 (70%) patients had severe knee arthritis and 9 (30%) patients had moderate to severe knee arthritis. After getting injection, there was satisfactory joint function among the 4 (13.3%) patients and 26 (86.7%) patients had mild to moderate knee arthritis according to Oxford Knee Score. Both VAS and Oxford Knee Score changed significantly 3 months after intra-articular corticosteroid injection. Conclusion: This present study concludes that intra-articular corticosteroid injection for osteoarthritis of knee produces significant pain relief for most patients even in severe cases and may provide better functional outcomes.

Keywords:

Knee; Osteoarthritis; Intra-articular injection; NSAIDs; Corticosteroid

Cite the Article:

Ghosh S, Islam Khan Z, Kumar Ghosh SR, Ali MR, Rahman F. Functional Outcome of Intra-Articular Corticosteroid Injections for Knee Osteoarthritis in Bangladeshi Patients. Ann Clin Case Rep. 2024; 9: 2592..