Journal Basic Info

  • Impact Factor: 1.809**
  • H-Index: 6
  • ISSN: 2474-1655
  • DOI: 10.25107/2474-1655
**Impact Factor calculated based on Google Scholar Citations. Please contact us for any more details.

Major Scope

  •  Lung Cancer
  •  Orthopedic Surgery
  •  Vascular Medicine
  •  Anesthesiology and Pain Medicine
  •  Renal Disease
  •  Physical Medicine & Rehabilitation
  •  Emergency Medicine and Critical Care
  •  Cardiology


Citation: Ann Clin Case Rep. 2024;9(1):2578.DOI: 10.25107/2474-1655.2578

Anaphylactic Shock Cased by Hemocoagulase Agkistrodon: A Case Report

Yu J1#, Wang Y1#, Jin L1 and Wang L2*

1Department of Anesthesiology, Chinese People's Liberation Army General Hospital 951, China
2Department of Anesthesiology and Perioperative Medicine, Xijing Hospital, Fourth Military Medical University, China
#These authors contributed equally to this work

*Correspondance to: Wang Lini 

 PDF  Full Text Case Report | Open Access


Hemocoagulase Agkistrodon, a thrombin-like enzyme derived from the venom of the Agkistrodon acutus snake, has been employed in clinical practice as a hemostatic agent. Herein, we report a case of anaphylactic shock triggered by hemocoagulase Agkistrodon. A 32-year-old woman underwent diagnostic dilation and curettage with cervical tissue biopsy procedure under general anesthesia and experienced anaphylactic shock following the postoperative administration of hemocoagulase. Instances of hemocoagulase Agkistrodon-induced anaphylactic shock were rarely documented. Therefore, unexplained gastrointestinal symptoms and hypotension in patients receiving hemocoagulase Agkistrodon should prompt consideration of this possibility.


Hemocoagulase Agkistrodon; Allergy; Anaphylactic Shock; Diagnostic dilation and curettage with cervical tissue biopsy procedure

Cite the Article:

Yu J, Wang Y, Jin L, Wang L. Anaphylactic Shock Cased by Hemocoagulase Agkistrodon: A Case Report. Ann Clin Case Rep. 2024; 9: 2578..

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