Atypical Multiple Aquagenic Syringeal Acrokeratoderma in a Patient Treatment with Botulinum Injection: A Case Report

Weng T1, He J1, Qi J1 and Yang Y2*

1Department of Dermatology, First Medical Center of Chinese PLA General Hospital, China
2Department of Dermatology, Third Medical Center of Chinese PLA General Hospital, China

^*Correspondance to: Yi Yang 

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Abstract:

Aquagenic Syringeal Acrokeratoderma (ASA), a rare transient disease that occurs after water immersion and disappears shortly after drying, is more commonly observed in young women, which mostly affects the palms, and to a lesser extent the feet. We reported a 40-year-old Asian man with 13-year history of erythema and pale brown flattened papules on hands with no involvement of palms which was diagnosed as ASA. Additionally, knees, elbows, buttocks, and ankles were involved in the presentation of dark red macules and patches. Uniquely, the lesions were worsened and durable than usual when the patient felt exhausted. Only botulinum toxin via subcutaneous injection with a concentration of 50 UI per 1 ml led to significant improvement. In addition, Dermoscopy was useful and utilized for diagnosis and follow-up observation

Keywords:

Aquagenic syringeal acrokeratoderma; Botulinum injection; Dermoscopy

Cite the Article:

Weng T, He J, Qi J, Yang Y. Atypical Multiple Aquagenic Syringeal Acrokeratoderma in a Patient Treatment with Botulinum Injection: A Case Report. Ann Clin Case Rep. 2023; 8: 2536..