Journal Basic Info

  • Impact Factor: 1.809**
  • H-Index: 6
  • ISSN: 2474-1655
  • DOI: 10.25107/2474-1655
**Impact Factor calculated based on Google Scholar Citations. Please contact us for any more details.

Major Scope

  •  Orthopedic Surgery
  •  Genetics
  •  Transplantation Medicine
  •  Pneumonia
  •  Tuberculosis
  •  Pharmacology and Therapeutics
  •  Respiratory Medicine
  •  ENT


Citation: Ann Clin Case Rep. 2023;8(1):2524.DOI: 10.25107/2474-1655.2524

Fundamental Cognizance and Scholarly Exploration of Immune-Related Notions in Head and Neck Squamous Cell Carcinoma (SCC) from 2012 to 2022: A Bibliometric Analysis

Miao R1,2*, Ma W3 and Liu S3

1Department of Otolaryngology Head and Neck Surgery, Xiangya Hospital, Central South University, China
2Otolaryngology Major Disease Research Key Laboratory of Hunan Province, China
3Harbin Medical University Cancer Hospital, China

*Correspondance to: Rui Miao 

 PDF  Full Text Research Article | Open Access


Background and Objective: Immunization holds profound research significance and promising application potential in the realm of Head and Neck Squamous Cell Carcinoma (HNSCC). Regrettably, only a paucity of bibliometric data has been dedicated to a systematic examination of this domain. The present study endeavors to holistically assess the research landscape encompassing immunization and allied concepts in HNSCC. It shall encompass an exhaustive review of countries, institutions, authors, and journals involved in this sphere, while also evaluating the knowledge framework through keyword co-occurrence analysis. Methods: The method employed for subject retrieval involved accessing the Web of Science core collection to obtain works and reviews concerning HNSCC immunity. Subsequently, bibliometric analysis was conducted utilizing the CiteSpace and VOSviewer software. Results: Between January 01st, 2012 and October 31st, 2022, a total of 1,744 English works and reviews were considered in the analysis. The research contributions emanated from 402 institutions, primarily from 57 countries and regions. In terms of journals, CANCERS published the highest number of works, other journals in the fields of molecular biology, biological immunology, and clinical medicine also made substantial contributions. Over the course of time, the landscape of research hotspots gracefully evolved. Certain illustrious terms such as “open label”, “T cell”, “immunotherapy”, and “tumor microenvironment” elegantly emerged, gracing the scholarly stage with their profound frequency. Conclusion: This study presents a thorough and all-encompassing assessment of HNSCC research within the context of immunity, achieved through the utilization of bibliometric and visualization methodologies. By offering insights into the dynamic evolution of immune-related concepts in HNSCC, this paper will undoubtedly aid researchers in gaining a deeper understanding of this complex domain.


Immunity; Head and neck squamous cell carcinoma; Bibliometric analysis; CiteSpace; VOSviewer

Cite the Article:

Miao R, Ma W, Liu S. Fundamental Cognizance and Scholarly Exploration of Immune-Related Notions in Head and Neck Squamous Cell Carcinoma (SCC) from 2012 to 2022: A Bibliometric Analysis. Ann Clin Case Rep. 2023; 8: 2524..

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