Kikuchi-Fujimoto's Disease: A Clinical Onset of Systemic Lupus Erythematosus

Garcia-Cerda D1, Zuno-Silva W1, Rivas-Casillas NC1, Vázquez-Camacho M1, Mendoza- Lujambio I1,2, Marín-Rosales M1,3 and Garcia-De la Torre I1,3*

1Department of Immunology and Rheumatology, Hospital General de Occidente, Mexico
2SEPI, Higher School of Medicine, Instituto Politécnico Nacional, Mexico
3Universidad de Guadalajara, Guadalajara, Jalisco, Mexico

^*Correspondance to: Ignacio Garcia-De la Torre 

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Abstract:

Kikuchi-Fujimoto's Disease (KFD), a benign infrequent idiopathic disorder, is suggested to correlate with viral infections and autoimmune disorders, such as Systemic Lupus Erythematosus (SLE). Cervical lymphadenopathy and constitutive symptoms are the cardinal KFD manifestations that could also be present in other diseases, including SLE. The overlap diagnosis between KFD and SLE needs high suspicion and a good understanding of both pathologies. This case report presents the case of a female patient presenting with bilateral submandibular adenopathy, right palpebral nodule, weight loss, night fever, node biopsy with histiocytic necrotizing lymphadenitis, and antinuclear antibodies 1:320 with speckled pattern (AC- 4) and positive anti-Sm and anti-nRNP/Sm.

Keywords:

Kikuchi-Fujimoto disease; Histiocytic necrotizing lymphadenitis; Systemic lupus erythematosus

Cite the Article:

Garcia-Cerda D, Zuno-Silva W, Rivas- Casillas NC, Vázquez-Camacho M, Mendoza-Lujambio I, Marín-Rosales M, et al. Kikuchi-Fujimoto's Disease: A Clinical Onset of Systemic Lupus Erythematosus. Ann Clin Case Rep. 2023; 8: 2518..