Severe Hypercalcemia in a Case of Rhabdomyolysis and AKI – Diagnostic and Therapeutic Dilemma

Shivam S1*, Himanshu VP1, Vivek BK1, Subho B1, Vishal P1, Vedprakash S1 and Vineet M2

1Department of Nephrology and Clinical Transplantation, Institute of Kidney Diseases and Research Center, Dr HL Trivedi Institute of Transplantation Sciences (IKDRC-ITS), India
2Department of Obstetrics and Gynecology, IKDRC-ITS, India

^*Correspondance to: Shivam N Shah 

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Abstract:

We report a case of 25-year-old male patient – with no comorbidities, having developed Rhabdomyolysis (RBD) - due to muscle injury following a fight and Acute Kidney Injury (AKI), who went on to develop severe Hypercalcemia during polyuric phase of AKI. Hypercalcemia in RBD is a relatively rare finding, with very few cases reported. Hypercalcemia is likely explained by systemic release of calcium phosphate salts deposited in the muscle following injury. Hypercalcemia can be very severe and symptomatic – as in present case and needs management on an urgent basis -especially to prevent arrhythmias and sudden death. It may need giving calcitonin, bisphosphonates, loop diuretics, aggressive hydration or hemodialysis – but is self-limiting, and in majority of cases - returns to normal within 8 to 10 days.

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Cite the Article:

Shivam S, Himanshu VP, Vivek BK, Subho B, Vishal P, Vedprakash S, et al. Severe Hypercalcemia in a Case of Rhabdomyolysis and AKI – Diagnostic and Therapeutic Dilemma. Ann Clin Case Rep. 2023; 8: 2479.