Journal Basic Info

  • Impact Factor: 1.809**
  • H-Index: 6
  • ISSN: 2474-1655
  • DOI: 10.25107/2474-1655
**Impact Factor calculated based on Google Scholar Citations. Please contact us for any more details.

Major Scope

  •  Palliative Care
  •  Hepatology
  •  Obstetrics and Gynecology
  •  Pediatrics
  •  Sleep Medicine and Disorders
  •  Respiratory Medicine
  •  Molecular Biology
  •  Breast Neoplasms


Citation: Ann Clin Case Rep. 2023;8(1):2406.DOI: 10.25107/2474-1655.2406

Neuro-Behcet Disease Presenting as a Bilateral Thalamic Infarct Secondary to Cerebral Vein Thrombosis and Multiple Cerebral Arteritis; A Case Report

Rabadon CR* and Juangco DN

Department of Neurosciences, East Avenue Medical Center, Philippines

*Correspondance to: Clinton R Rabadon 

 PDF  Full Text Case Report | Open Access


Background: Behcet’s Disease is a systemic autoimmune disease characterized by chronic inflammation primarily affecting the eyes, mouth, and genitals. Its prevalence is very rare in Southeast Asia with only 31 recorded cases from 1988 to 2014 in a cluster of rheumatology clinics. The involvement of the central nervous system in Bechet’s Disease is termed as Neuro Behcet’s Disease, with a prevalence of 4% to 9%. However, prevalence of Neuro-Behcet disease in female is uncommon. CNS involvement mimics other conditions such as neoplasm, infection, and stroke. Herein, we report a rare case of Neuro-Behcet disease who presented with bilateral thalamic infarct from deep cerebral vein thrombosis and arteritis. Case Report: A 34-year-old Filipino female was admitted to our hospital due to progressive headache and somnolence with a significant history of recurrent genital ulcers and arthritis. Her CT scan showed ischemic stroke on bilateral thalami with MRI and vascular study of subacute hemorrhagic conversion from thrombosis on vein of Galen and straight sinus with multiple segmental arteritis. Other causes of thrombosis such as neoplasm, cardiovascular etiology, and other autoimmune diseases were ruled out. Due to the absence of pathognomonic laboratory features, the patient was diagnosed with Neuro-Behcet’s Disease after satisfying the clinical criteria. Clinical and radiographic improvement was noted after initiation of treatment with steroid, azathioprine, and anti-coagulant. Conclusion: These findings suggest that the patient’s bilateral thalamic infarct could have been due to cerebral vein thrombosis and segmental arteritis as a rare complication of Neuro-Behcet Disease.


Cite the Article:

Rabadon CR, Juangco DN. Neuro- Behcet Disease Presenting as a Bilateral Thalamic Infarct Secondary to Cerebral Vein Thrombosis and Multiple Cerebral Arteritis; A Case Report. Ann Clin Case Rep. 2023; 8: 2406..

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