The Increased Glucose Level in Sputum Sample of the COVID-19 Patients with Positive CT Scan: A New Method for Detection of the Lung Inflammation

Mohammad Ali Khayamian1,2, Mohammadreza Ghaderinia1,2, Hossein Simaee1,2, Hamed Abadijoo1,2, Seyed Mojtaba Yazdanparast1,2, Parisa Hosseinpour3, Hassan Sanati4, Mohammad Ghaffari5, Atefeh Abedini6 and Mohammad Abdolahad1,2,7*

1Nano Bioelectronics Devices Lab, Cancer Electronics Research Group, School of Electrical and Computer Engineering, University of Tehran, Iran
2Nano Electronic Center of Excellence, Nano Bio Electronics Devices Lab, School of Electrical and Computer Engineering, University of Tehran, Iran
3SEPAS Pathology Laboratory, Iran
4ATMP Department, Breast Cancer Research Center, Motamed Cancer Institute, Iran
5Department of Family Medicine, School of Medicine, Iran University of Medical Sciences, Iran
6Chronic Respiratory Diseases Research Center, National Research Institute of Tuberculosis and Lung Diseases, Shahid Beheshti University of Medical Sciences, Iran
7Cancer Institute, Imam-Khomeini Hospital, Tehran University of Medical Sciences, Iran

^*Correspondance to: Mohammad Abdolahad 

 PDF  Full Text Short Communication | Open Access

Abstract:

An increase in the glucose level in the sputum sample of the COVID-19 patients was analyzed as a diagnostic factor for the presence of inflammation in the patients suspicious of COVID-19 disease. During the immunological phase of COVID-19, a cytokine storm causes the dilation of the vessels around the alveoli in the lung, and consequently, the blood is leaked into the air sacs. This inflammatory phase and the probability of lung involvement are currently detected using the chest CT scan. We have, for the first time, measured the glucose level in the sputum sample of the COVID-19 patients and compared it with the data of the CT scan. The results revealed a meaningful increase in the sputum glucose of the patients with positive CT compared to those in negative cases. We believe that the measurement of the sputum sample could offer a cheap, simple, and fast method of diagnostics for screening patients with inflammation, especially in medical centers without access to CT scan machines.

Keywords:

Cite the Article:

Ali Khayamian M, Ghaderinia M, Simaee H, Abadijoo H, Mojtaba Yazdanparast S, Hosseinpour P, et al. The Increased Glucose Level in Sputum Sample of the COVID-19 Patients with Positive CT Scan: A New Method for Detection of the Lung Inflammation. Ann Clin Case Rep. 2022; 7: 2308.