Journal Basic Info

  • Impact Factor: 1.809**
  • H-Index: 6
  • ISSN: 2474-1655
  • DOI: 10.25107/2474-1655
**Impact Factor calculated based on Google Scholar Citations. Please contact us for any more details.

Major Scope

  •  Transplantation Medicine
  •  Breast Neoplasms
  •  Signs and Symptoms-Clinical Findings
  •  Sleep Medicine and Disorders
  •  Medical Radiography
  •  Physical Medicine & Rehabilitation
  •  Tuberculosis
  •  Gastric Cancer


Citation: Ann Clin Case Rep. 2021;6(1):2065.DOI: 10.25107/2474-1655.2065

What is the Effect of Apple Juice Intake on Oxidative Stress and Serum Potassium Levels after a Single Hemodialysis Session? A Pioneer - Pilot Study

Andréia G Giaretta1, Mayara Lopes Martins1, Taís T Silveira1, Francilene GK Vieira1, Edson L da Silva1,2 and Elisabeth Wazlawik1*

1Postgraduate Program in Nutrition, Federal University of Santa Catarina, Brazil
2Department of Clinical Analyses, Federal University of Santa Catarina, Brazil

*Correspondance to: Elisabeth Wazlawik 

 PDF  Full Text Case Report | Open Access


affecting serum Potassium (K) levels in Hemodialysis (HD) patients. We aim to analyze the effect of Fuji Apple Juice (AJ) intake on Oxidative Stress (OS) and biochemical parameters after a single HD session in chronic HD patients. Case Report: Six HD patients consumed 300 mL and 150 mL of Fuji AJ (Malus domestica Borkh) on different days, immediately after a single HD session. A 3-week washout period was applied between the two doses. Blood samples were collected before and after 30 min and 60 min. We analyzed the total antioxidant status, Total Oxidant Status (TOS), Ascorbic Acid (AA), catalase, glutathione peroxidase, Superoxide Dismutase (SOD), and reduced glutathione, as well as biochemical parameters including phosphorus, K, Uric Acid (UA), and glucose. After both trials, patients were questioned by telephone about AJ tolerance. Conclusion: The 300 mL of AJ significantly increased TOS (p=0.05), AA (p=0.001), UA, and K levels (p ≤ 0.00) over time, while SOD activity increased significantly only after 30 min (p=0.02). After 150 mL of AJ, UA and phosphorus levels increased significantly (p<0.00). Acute AJ intake did not affect bowel habits and no adverse gastrointestinal events were reported. Thus, acute AJ intake was well tolerated and 300 mL of AJ may provide mild-favorable effects on antioxidant status without exceeding recommended values of serum K in HD patients.


Hemodialysis; Apple juice; Acute intake; Oxidative stress; Potassium

Cite the Article:

Giaretta AG, Martins ML, Silveira TT, Vieira FGK, da Silva EL, Wazlawik E. What is the Effect of Apple Juice Intake on Oxidative Stress and Serum Potassium Levels after a Single Hemodialysis Session? A Pioneer - Pilot Study. Ann Clin Case Rep. 2021; 6: 2065..

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