Journal Basic Info

  • Impact Factor: 1.809**
  • H-Index: 6
  • ISSN: 2474-1655
  • DOI: 10.25107/2474-1655
**Impact Factor calculated based on Google Scholar Citations. Please contact us for any more details.

Major Scope

  •  Diabetology
  •  Nuclear Medicine
  •  Orthopedic Sugery
  •  Endocrinology
  •  Asthma
  •  Orthopedic Surgery
  •  Urology Cases
  •  Endoscopy

Abstract

Citation: Ann Clin Case Rep. 2019;4(1):1776.DOI: 10.25107/2474-1655.1776

Spinal Tuberculosis - Treatment Options Beyond Guidelines

Inês Esteves Cruz, Pedro Ferreira, Sara Brandão Machado, João Mourato Torres, Cláudia Miranda and Isabel Antunes

Hospital de Egas Moniz, Centro Hospitalar de Lisboa Ocidental, Portugal Hospital de Santa Maria, Centro Hospitalar Lisboa Norte, Portugal

*Correspondance to: InĂªs Esteves Cruz 

 PDF  Full Text Case Report | Open Access

Abstract:

Spinal tuberculosis, a presentation of extrapulmonary tuberculosis, usually presents with chronic back pain or deformity. The diagnosis is often delayed due to the insidious and nonspecific nature of the initial symptoms. The thoracic spine is more commonly affected, but it can affect other segments or be multisegmental. The site and extent of the lesion will determine the resulting neurological deficits which can lead to significant morbidity and functional impairment. Combination chemotherapy for 6 months is recommended, but some experts may recommend therapy for 9 to 12 months depending on the circumstances. Adjunct corticotherapy and surgery are also options in specific cases. Further studies will be needed in order to better understand the role of these therapies in severe tuberculosis, and in particular spinal tuberculosis. Learning Points • Neurologic abnormalities appear in 10% to 27% of cases and can be associated with significant morbidity and functional impairment. • Expert opinion supports the extension of combined chemotherapy for 9 to 12 months in selected cases. • Extended combined chemotherapy and adjunct corticotherapy might be considered in spinal tuberculosis with evidence of cord compression and severe neurological compromise. • Patients with severe neurological impairment due to tuberculous spondylitis may have a good prognosis.

Keywords:

Tuberculosis; Spinal tuberculosis; Spinal cord compression; Paraplegia; Corticosteroid therapy; Mycobacterium tuberculosis

Cite the Article:

Cruz IE, Ferreira P, Machado SB, Torres JM, Miranda C, Antunes I. Spinal Tuberculosis - Treatment Options Beyond Guidelines. Ann Clin Case Rep. 2019; 4: 1776..

Search Our Journal

Journal Indexed In

Articles in PubMed

A New Minimally Invasive Procedure for Muscle, Back, Neck Pain and Radiculopathy - The Myofascial Nerve Block
 PubMed  PMC  PDF  Full Text
Tocotrienols: Exciting Biological and Pharmacological Properties of Tocotrienols and Naturally Occurring Compounds, Part II
 PubMed  PMC  PDF  Full Text
View More...

Articles with Grants

Evaluate the Existing Integration of Sexual Reproductive Health Services with HIV Treatment in Oromia Regional
 Abstract  PDF  Full Text
Familial Hypercholesterolemia with Cardiovascular Disease: A Case Report
 Abstract  PDF  Full Text
View More...