Neuroleptic Malignant Syndrome without Hyperthermia Induced by Aripiprazole Extended-Release Injection

Ilario C, Sentissi O and Coste C

Department of Mental Health and Psychiatry, University Hospital of Geneva, Switzerland

^*Correspondance to: Sentissi O 

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Abstract:

Neuroleptic malignant syndrome may be considered an idiosyncratic neurological condition with potentially lethal consequences associated with the assumption of all antipsychotics, first described in the early sixties in association with the antipsychotic haloperidol. Recently, several cases of the syndrome have been reported in literature as a complication of typical and atypical antipsychotic drugs. Moreover, a widespread use of antipsychotics in numerous neuropsychiatric disorders has lead to the analysis of the risks and consequences of neuroleptic malignant syndromes. This case report describes the occurrence of a neuroleptic malignant syndrome in a 55-year-old woman with intellectual disability presenting with organic delusional disorder, following administration of aripiprazole extended-release injection. Although cases of neuroleptic malignant syndrome induced by aripiprazole or by atypical antipsychotics extended-release have been published in literature, this is the first case report regarding a neuroleptic malignant syndrome induced by aripiprazole extended-release injection.

Keywords:

Neuroleptic malignant syndrome (NMS); Aripiprazole extended-release injection; Antipsychotic drugs

Cite the Article:

Ilario C, Sentissi O, Coste C. Neuroleptic Malignant Syndrome without Hyperthermia Induced by Aripiprazole Extended-Release Injection. Ann Clin Case Rep. 2017; 2: 1372.