Abstract || Annals of Clinical Case Reports

Major Scope

Cardiovascular Case Reports
Oncology Case Reports
Surgical Case Reports
Gastroenterological Case Reports
Neurological Case Reports
Dermatological Case Reports
Respiratory Case Reports
Obstetrics/Gynecology Case Reports
Nephrology Case Reports
Immunology Case Reports
Paediatric Case Reports
Orthopedics Case Reports
Dental Case Reports

Abstract

Citation: Ann Clin Case Rep. 2016;1(1):1190.DOI: 10.25107/2474-1655.1190

Retinoblastoma and Second Bone Sarcomas: A Pediatric Case Report

Zied Jlalia, Aymen Zaier, Samih Kacem and Mahmoud Smida

Kassab Orthopedics Institute, Medicine Faculty of Tunis, University of El Manar, Tunisia

^*Correspondance to: Zied Jlalia

PDF Full Text Case Report | Open Access

Abstract:

The occurrence of secondary malignant neoplasia remains the most important long-term risk but rare of retinoblastoma. Osteosarcoma represents the most frequent second malignant tumor. We report here a case of a right femur osteosarcoma in a 7 years and half old-boy after being treated for retinoblastoma at two years of age. The treatment consisted of chemotherapy and conservative surgery with intercalary tumor resection and reconstruction by two autologous fibulas. Three years after, the child died from pleural metastasis.The purpose of this report is to review the genetic relationship between retinoblastoma and osteosarcoma and to discuss treatment protocol for the latter.