Ann Clin Case Rep | Volume 7, Issue 1 | Research Article | Open Access

Spectrum of Imaging Findings of Rhino-Orbital-Cerebral Mucormycosis during COVID-19 Pandemic: A Case Series Study

Mahesh Byale* and Rohini Pattanshetti

Department of Radiodiagnosis, S. Nijalingappa Medical College and Research Institute, India

*Correspondance to: Mahesh Byale 

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Purpose: Imaging study on Rhino-Orbital-Cerebral Mucormycosis (ROCM) in post COVID-19 patients with combined Computed Tomography (CT) and Magnetic Resonance Imaging (MRI) studies. Materials and Methods: A retrospective study of 17 patients who developed ROCM in post COVID-19 infection treated with steroids, Remdesivir or oxygen for the spectrum of imaging studies was conducted. Several clinical parameters viz., RTPCR status, clinical history, diabetic and vaccination status and analysis by combined CT and MR imaging was carried to outline the fungal disease. ROCM was confirmed by either KOH mount or histopathological investigations followed by Amphotericin B and Functional Endoscopic Sinus Surgery (FESS). Results: In a survey of 17 patients aged 35 to 65 years, men (76.47%) were more affected than women (23.53%). CT and MRI showed involvement of the bilateral paranasal sinuses in all patients (100%), and the major involvement of the ethmoid sinuses in 76.47% of patients and the maxillary sinuses in 94.11% of patents. The incidence of disease to orbit was 58.82%, with right and left involvement at 5.88% and 52.94%, respectively. Both orbital extensions were seen at 5.88% and optic nerve involvement at 23.529%. Cavernous sinus disease, meningeal association and brain parenchymal extension were observed in 11.764%, 58.823% and 5.882%, respectively. Conclusion: Clinicians and practitioners should be aware of the possibility of ROCM after COVID-19 infection and the combined use of CT and MR imaging. Identifying the disease in the early stages through CT and MRI imaging plays an important role in effective treatment.


Rhino-orbital-cerebral mucormycosis; COVID-19: Computed tomography: Magnetic resonance imaging


Byale M, Pattanshetti R. Spectrum of Imaging Findings of Rhino-Orbital- Cerebral Mucormycosis during COVID-19 Pandemic: A Case Series Study. Ann Clin Case Rep. 2022; 7: 2211..

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