Ann Clin Case Rep | Volume 7, Issue 1 | Case Report | Open Access

Thrombocytopenia after Splenectomy: A Case Report

Yajun Zhang, Jun Li, Cheng Tian, Zhenyu Fan and Jilin Cheng*

Department of Gastroenterology and Hepatology, Fudan University, China

*Correspondance to: Jilin Cheng 

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Background: Thrombocytopenia is the most common hematologic complication associated with advanced liver disease. It has important clinical significance. There are many causes of thrombocytopenia. Abnormal distribution of platelets in spleen and decreased production of thrombopoietin are the main mechanisms. Splenectomy is an effective treatment for these patients. However, recurrent thrombocytopenia after splenectomy is very rare. Case Summary: We report a case of a 59-year-old female patient. The patient had a history of autoimmune cirrhosis for more than 10 years. Splenectomy was performed for thrombocytopenia. But thrombocytopenia recurred about two weeks after splenectomy. After we ruled out the accessory spleen as a possible cause, the platelet count of the patient returned to normal after treatment with anti-infection, hormone, thrombopoietin and platelet transfusion. Conclusion: For patients after splenectomy, we should be vigilant against recurrent thrombocytopenia caused by infection, accessory spleen, immunity, drugs and other related reasons.


Splenectomy; Thrombocytopenia; Accessory spleen; Immune; Infection; Drugs


Zhang Y, Li J, Tian C, Fan Z, Cheng J. Thrombocytopenia after Splenectomy: A Case Report. Ann Clin Case Rep. 2022; 7: 2185..

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