Ellen He and Sven Skog*
Department of Medicine, Shenzhen Ellen-Sven Precision Medicine Institute, ChinaFulltext PDF
Background: Serum Thymidine Kinase 1 Concentration (STK1p) is benefit for a long-term followup of cancer patients. Aim: To determine the store time of serum thymidine kinase 1 at -20ºC. Methods: The STK1p were determined by chicken anti-human TK1-IgY-polyclonal antibodies. Results: The data of STK1p were analyzed from serum samples (n=109) in breast, lung and head & neck malignant patients at -20ºC. The samples (n=69), randomly collected from the cohort of 109 samples were reanalyzed. No significant changes in STK1p values were found (p＞0.2). Conclusion: Store at -20°C did not affect the quality of thymidine kinase 1 serum significant and thus make it possible for a long-term follow-up of the cancer patients or early tumour risk progress.
Thymidine kinase 1; Serum Thymidine Kinase 1 concentration (STK1p); Serum samples
He E, Skog S. Quality Changes of Deep-Freeze Serum Thymidine Kinase 1. Ann Clin Case Rep. 2022; 7: 2136..