Ann Clin Case Rep | Volume 7, Issue 1 | Short Communication | Open Access

Quality Changes of Deep-Freeze Serum Thymidine Kinase 1

Ellen He and Sven Skog*

Department of Medicine, Shenzhen Ellen-Sven Precision Medicine Institute, China

*Correspondance to: Sven Skog 

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Background: Serum Thymidine Kinase 1 Concentration (STK1p) is benefit for a long-term followup of cancer patients. Aim: To determine the store time of serum thymidine kinase 1 at -20ºC. Methods: The STK1p were determined by chicken anti-human TK1-IgY-polyclonal antibodies. Results: The data of STK1p were analyzed from serum samples (n=109) in breast, lung and head & neck malignant patients at -20ºC. The samples (n=69), randomly collected from the cohort of 109 samples were reanalyzed. No significant changes in STK1p values were found (p>0.2). Conclusion: Store at -20°C did not affect the quality of thymidine kinase 1 serum significant and thus make it possible for a long-term follow-up of the cancer patients or early tumour risk progress.


Thymidine kinase 1; Serum Thymidine Kinase 1 concentration (STK1p); Serum samples


He E, Skog S. Quality Changes of Deep-Freeze Serum Thymidine Kinase 1. Ann Clin Case Rep. 2022; 7: 2136..

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