Ann Clin Case Rep | Volume 6, Issue 1 | Case Report | Open Access

Amyloidosis as a Manifestation of POEMS Syndrome: Report of a Clinical Case

Sergio Alberto Mendoza-Álvarez1, Carlos González-Núñez1, Nydia Karen Cruz-Escutia1* and Aline Guillermina Ramírez-Alvarado2

1Department of Internal Medicine, High Specialty Medical Unit "Dr. Antonio Fraga Mouret", National Medical Center "La Raza", Mexican Social Security Institute, Mexico 2Department of Hematology, High Specialty Medical Unit "Dr. Antonio Fraga Mouret", National Medical Center "La Raza", Mexican Social Security Institute, Mexico

*Correspondance to: Nydia Karen Cruz-Escutia 

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Abstract

POEMS syndrome was first established in 1980 by Bardwick, referring to the presence of polyneuropathy, organomegaly, endocrinopathy, M protein, skin changes, as part of a manifestation of an underlying plasma cell neoplasm. To our knowledge there are few reports with cardiac involvement in POEMS syndrome, where chemotherapy has shown to reverse such involvement. We report a clinical case with cardiac amyloidosis and POEMS syndrome. On the other hand, amyloidosis turns out to be an infrequent entity that is the product of the deposit of an abnormal protein (Amyloid), which interferes with the functioning of the affected organ by producing deposit. The patient we present is of particular interest because he has the presence of both pathologies, we consider that the discussion in this clinical case implies a probable better prognosis of amyloidosis if it is associated with POEMS syndrome.

Keywords:

Amyloidosis; Paraneoplasic; POEMS syndrome

Citation:

Mendoza-Álvarez SA, González-Núñez C, Cruz-Escutia NK, Ramírez-Alvarado AG. Amyloidosis as a Manifestation of POEMS Syndrome: Report of a Clinical Case. Ann Clin Case Rep. 2021; 6: 2051..

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