Catherine Teskin*, Nikita Donti, Kunal Bhagat and Eric Russell
Department of Internal Medicine, Christiana Care Health System, USAFulltext PDF
Objective: Review the presentation of IgA vasculitis, associated complications, and treatment. Methods: We present laboratory findings and treatment related to this case, as well as, review of relevant literature. Results: Seventy year-old male with a past medical history of gout recently restarted on allopurinol who presented with maculopapular lesions. Initial lab work was remarkable for acute kidney injury and urine analysis revealing proteinuria. Rheumatology was consulted and workup included elevated IgA, undetectable rheumatoid factor, cryoglobulinemia not present HIV/hepatitis panel negative, urine drug screen negative for cocaine, low C3, negative ENA panel, negative ANCA panel, and negative MPO/PR3 antibodies. A biopsy of a characteristic lesion of the skin revealed strong deposits of IgA leading to the diagnosis of IgA vasculitis. Conclusion: This case demonstrates the importance of obtaining a biopsy, controversial benefit of steroids, and poorer prognosis with adults.
IgA vasculitis; Henoch-Schonlein purpura; Palpable purpura; Renal dysfunction
Teskin C, Donti N, Bhagat K, Russell E. Case of Adult-Onset IgA Vasculitis. Ann Clin Case Rep. 2020; 5: 1805.