Endoscopic Resection of a Large Brunner's Gland Hamartoma: A Case Report and Literature Review

Yu Jin, Gangping Li, Nan Shen, Weibin Chen, Xiaohua Hou and Jun Liu

Division of Gastroenterology, Huazhong University of Science and Technology, China Department of Radiology, Huazhong University of Science and Technology, China Department of Pathology, Huazhong University of Science and Technology, China

^*Correspondance to: Xiaohua Hou 

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Abstract:

Background: Brunner’s gland Hamartoma is a rare and benign tumor of the duodenum. Endoscopic resection of large Brunner’s gland Hamartoma has seldom been reported. We report a case of a Brunner’s gland Hamartoma which was as large as 6 cm × 5 cm that was successfully managed by endoscopic excision. Case presentation: A 49-year-old Chinese woman presented to a local hospital with a 5-month history of epigastric fullness and nausea. In local hospital, upper endoscopy presented a sessile lesion in the proximal duodenum, for which mucosal biopsies were non-diagnostic. She was managed conservatively; however, the patient did not improve over the next 2 months and complained of persistent epigastric fullness. Then she was referred to our hospital for further examination. In our hospital, the contrast-enhanced Computed Tomography (CT) showed a round mass about 5 cm in diameter. Endoscopic Ultrasonography (EUS) suggested this was a submucosal and cyst-solid lesion with a well-defined boundary, and there were no ulcers or erosions on the surface. Finally, the lesion was successfully managed by endoscopic technique (Endoscopic Submucosal Dissection, ESD). The size of the resected specimen was as large as 6 cm × 5 cm and pathologically diagnosed as Brunner’s gland Hamartoma. These results show that large Brunner’s gland Hamartoma can be treated successfully by careful use of endoscopic procedures. Conclusion: We present this case and reviewed the reported cases of Brunner’s gland hamartomas which were resected endoscopically, which might provide a reference for endoscopists and surgeons.

Keywords:

Duodenum; Brunner&39;s gland hamartoma; Endoscopic Resection

Cite the Article:

Jin Y, Li G, Shen N, Chen W, Hou X, Liu J. Endoscopic Resection of a Large Brunner's Gland Hamartoma: A Case Report and Literature Review. Ann Clin Case Rep. 2020; 5: 1785..