Ann Clin Case Rep | Volume 4, Issue 1 | Case Report | Open Access

Misdiagnosis of an Atypical Creutzfeldt-Jakob Disease: Analysis of One Case in China and Review of the Literature

Mengqi Zhanga1, Zigao Wangb2, Lijie Duana1 and Hengbing Zua1*

1Department of Neurology, Jinshan Hospital, Fudan University, China
2Department of Neurology, Huashan Hospital, Fudan University, China

*Correspondance to: Hengbing Zua 

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Creutzfeldt-Jakob Disease (CJD) is a fatal and infectious disease, which usually has atypical clinical symptoms include rapidly progressive dementia, myoclonus, pyramidal/extrapyramidal, visual, and akinetic mutism. In this report, we present an atypical sporadic Creutzfeldt-Jakob disease patient who was first misdiagnosed as encephalitis or brucellosis. In clinical study, for atypical CJD, it is very important to increase diagnosis accuracy and decrease misdiagnosis of CJD.


Creutzfeldt-Jakob disease; Prion protein; Dementia


Zhanga M, Wangb Z, Duana L, Zua H. Misdiagnosis of an Atypical Creutzfeldt- Jakob Disease: Analysis of One Case in China and Review of the Literature. Ann Clin Case Rep. 2019; 4: 1764.

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