Journal Basic Info

  • Impact Factor: 1.809**
  • H-Index: 6
  • ISSN: 2474-1655
  • DOI: 10.25107/2474-1655
**Impact Factor calculated based on Google Scholar Citations. Please contact us for any more details.

Major Scope

  •  Palliative Care
  •  Oncology Cases
  •  Epidemiology
  •  Cardiac Surgery
  •  Pathology
  •  Renal Disease
  •  ENT
  •  Family Medicine and Public Health

Abstract

Citation: Ann Clin Case Rep. 2018;3(1):1511.DOI: 10.25107/2474-1655.1511

Diffuse Cutaneous Mastocytosis

Gerda Petersone, Sanita Zigure and Aleksejs Zavorins

Department of Dermatology, Riga Stradin’s University, Lativa
Children’s Clinical University Hospital Riga, Lativa

*Correspondance to: Gerda Petersone 

 PDF  Full Text Case Report | Open Access

Abstract:

Mastocytosis is a group of disorders characterized by abnormal accumulation of mast cells in the skin and other organs. Diffuse cutaneuos mastocytosis is a rare and most severe variant of cutaneous mastocytosis. In this article, we present you a girl with urtical elements on her skin folds, abdomen and axillae since she was 4 month old that progressed into generalized vesiculobullos rash with positive Darrier’s sign. Based on clinical, histological and laboratorial findings the diagnosis of diffuse cutaneous mastocytosis was made at the age of 6 months. Treatment was started at age of 4 months with cetirizine, after the diagnosis was made we increased dose four times, later desloratadine, topical zinc preparations, topical pimecrolimus, montelukast was added but there was no therapeutical effect so at age of 7 months she started therapy with oral glucocorticosteroids. At age of 17 months she started oral cromolyn sodium. This is the first case of DCM in Children’s Clinical University hospital Riga as far as we know.

Keywords:

Cite the Article:

Petersone G, Zigure S, Zavorins A. Diffuse Cutaneous Mastocytosis. Ann Clin Case Rep. 2018; 3: 1511.

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