A Newborn with Pulmonary Atresia and Antenatal Colchicine Exposure

Fırat Ergin, Demet Terek, Mehmet Yalaz, Ertürk Levent, Özge Altun Köroğlu, Sibel Göksel, Mete Akısü, Ferda Özkınay and Nilgün Kültürsay

Department of Pediatrics, Division of Neonatology, Ege University, Turkey
Department of Pediatrics, Division of Cardiology, Ege University, Turkey
Department of Pharmacology, Ege University, Turkey
Department of Pediatrics, Division of Genetics, Ege University, Turkey

^*Correspondance to: Nilgün Kültürsay 

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Abstract:

Colchicine treatment improved female fertility and the outcome of pregnancy in Familial Mediterranean Fever patients by preventing the serosal adhesions and controlling the acute attacks. Limited number of human series does not show any proof for increased abortus, stillbirth or teratogenic effect of colchicine. Here we present a term newborn with pulmonary atresia whose mother was on colchicine during pregnancy. These two events may be coincidentally related; however, there may be a causal relationship that has not been reported in the literature yet. Fetal echocardiography is strongly recommended for women who are pregnant and taking colchicine.

Keywords:

Colchicine; Teratogen; Newborn; Heart defect; Pulmonary atresia

Cite the Article:

Ergin F, Terek D, Yalaz M, Levent E, Köroğlu ÖA, Göksel S, et al. A Newborn with Pulmonary Atresia and Antenatal Colchicine Exposure. Ann Clin Case Rep. 2017; 2: 1284.