A Case of Primary Retroperitoneal Serous Adenocarcinoma and Literature Review

Meng-meng Zhang, Xi-wa Zhao and Jian Zhao, Shan Kang

Department of Obstetrics and Gynaecology, Hebei Medical University, China

^*Correspondance to: Shan Kang 

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Abstract:

Primary retroperitoneal serous adenocarcinoma (PRSA) is an extremely rare clinical entity with only seven cases previously reported. In this article, we described a 58-year-old woman with a solitary tumor of serous adenocarcinoma located in the right side of the Douglas Pouch arising from the retroperitoneum. Although several theories have been proposed, the exact origin of PRSA remains unclear. The most widely accepted theory is caelomic metaplasia. According to the histopathological results of the present case, the concept of caelomic metaplasia has been proved to a certain extent. As far as we know, this may be the first case which provides a direct and potent evidence for this theory and is conductive to explain the histogenesis of PRSA. The patient underwent a treatment modality combining complete surgical resection with platinum-based chemotherapy, which is extremely likely to contribute to an excellent clinical outcome, and we consider that such therapeutic strategy may be the preferred method for the treatment of PRSA.

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Cite the Article:

Meng-meng Zhang, Xi-wa Zhao, Zhao J, Kang S. A Case of Primary Retroperitoneal Serous Adenocarcinoma and Literature Review. Ann Clin Case Rep. 2017; 2: 1277.