Syncopal Episode as a Result of Elevated Ammonia Levels: A Case Report

Abuagla Q, Aljaberi M and Calvello E

Tawam Hospital, United Arab Emirates University, UAE

^*Correspondance to: Abuagla Q 

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Abstract:

Valproic acid is an increasingly common medication used as an anticonvulsant, a mood stabilizer and in the prophylaxis of migraine headaches. Generally, Valproic Acid (VPA) is well tolerated, with a favorable safety profile. Serious adverse reactions such as hepatic failure, pancreatitis, thrombocytopenia, and hyperammonemic encephalopathy are rare. While the incidence of VPA– induced hyperammonemic encephalopathy is unknown, it can progress to fatal outcome without early recognition and appropriate treatment. We present a case of VPA- induced hyperammonemia in an epileptic patient presenting with a chief complaint of syncope and confusion.

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Cite the Article:

Abuagla Q, Aljaberi M, Calvello E. Syncopal Episode as a Result of Elevated Ammonia Levels: A Case Report. Ann Clin Case Rep. 2017; 2: 1260.